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Anti-KMT2C Polyclonal Antibody

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Catalog No. TMAB-01032
Alias Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog, Myeloid/lymphoid or mixed-lineage leukemia protein 3, MLL3, Lysine N-methyltransferase 2C, KMT2C, Homologous to ALR protein, Histone-lysine N-methyltransferase MLL3

Anti-KMT2C Polyclonal Antibody is a Rabbit antibody targeting KMT2C. Anti-KMT2C Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-KMT2C Polyclonal Antibody

Anti-KMT2C Polyclonal Antibody

😃Good
Catalog No. TMAB-01032Alias Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog, Myeloid/lymphoid or mixed-lineage leukemia protein 3, MLL3, Lysine N-methyltransferase 2C, KMT2C, Homologous to ALR protein, Histone-lysine N-methyltransferase MLL3
Anti-KMT2C Polyclonal Antibody is a Rabbit antibody targeting KMT2C. Anti-KMT2C Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2217-10 days
100 μL$3747-10 days
200 μL$5297-10 days
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Product Introduction

Bioactivity
Description
Anti-KMT2C Polyclonal Antibody is a Rabbit antibody targeting KMT2C. Anti-KMT2C Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
SynonymsMyeloid/lymphoid or mixed-lineage leukemia protein 3 homolog, Myeloid/lymphoid or mixed-lineage leukemia protein 3, MLL3, Lysine N-methyltransferase 2C, KMT2C, Homologous to ALR protein, Histone-lysine N-methyltransferase MLL3
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Pig)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (mouse testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (KMT2C) Polyclonal Antibody, Unconjugated (TMAB-01032) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityHighly expressed in testis and ovary, followed by brain and liver. Also expressed in placenta, peripherical blood, fetal thymus, heart, lung and kidney. Within brain, expression was highest in hippocampus, caudate nucleus, and substantia nigra. Not detect
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human KMT2C
Antigen Species
Human
Gene Name
KMT2C
Gene ID
Protein Name
Histone-lysine N-methyltransferase 2C
Uniprot ID
Function
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/MLL3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
Chemical Properties
Molecular WeightTheoretical: 541 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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