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Biotin-PEG4-Picolyl azide

Name: Biotin-PEG4-Picolyl azide
Brand: TargetMol
SKU: T17587
Price: 108 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T17587Cas No. 2222687-71-8

Biotin-PEG4-Picolyl azide is a PROTAC linker belonging to the class of PEGs that can be used to synthesize PROTAC molecules.

Biotin-PEG4-Picolyl azide

🥰Excellent

Purity: 97.71%

Catalog No. T17587Cas No. 2222687-71-8

Biotin-PEG4-Picolyl azide is a PROTAC linker belonging to the class of PEGs that can be used to synthesize PROTAC molecules.

Pack Size	Price	Availability
1 mg	$108	In Stock
5 mg	$272	In Stock
10 mg	$438	In Stock
25 mg	$696	In Stock
50 mg	$982	In Stock

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Batch Information

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Purity:97.71%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Biotin-PEG4-Picolyl azide is a PROTAC linker belonging to the class of PEGs that can be used to synthesize PROTAC molecules.
In vitro	PROTACs are compounds composed of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1].

Chemical Properties

Molecular Weight	622.74
Formula	C₂₇H₄₂N₈O₇S
Cas No.	2222687-71-8
Smiles	C(CCCC(NCCOCCOCCOCCOCCC(NC=1C=CC(CN=[N+]=[N-])=NC1)=O)=O)[C@H]2[C@@]3([C@](CS2)(NC(=O)N3)[H])[H]
Relative Density.	no data available
Color	Yellow
Appearance	Oil

Storage & Solubility Information

Storage

store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120 mg/mL (192.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6058 mL	8.0290 mL	16.0581 mL	80.2903 mL
5 mM	0.3212 mL	1.6058 mL	3.2116 mL	16.0581 mL
10 mM	0.1606 mL	0.8029 mL	1.6058 mL	8.0290 mL
20 mM	0.0803 mL	0.4015 mL	0.8029 mL	4.0145 mL
50 mM	0.0321 mL	0.1606 mL	0.3212 mL	1.6058 mL
100 mM	0.0161 mL	0.0803 mL	0.1606 mL	0.8029 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc