keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shepherdin is a synthetic peptide mirroring amino acids 79-87 of human survivin, acting as an inhibitor of the survivin-heat shock protein 90 (Hsp90) interaction. It specifically targets the N-terminal domain of Hsp90, blocking the survivin-Hsp90 interaction in human reticulocyte extracts at a 150 µM concentration. Conjugates of Shepherdin with cell-permeable peptides, such as penetratin or the HIV Tat sequence, exhibit anticancer properties both in vitro and in vivo.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 55.00 | |
5 mg | Inquiry | $ 197.00 | |
10 mg | Inquiry | $ 376.00 | |
25 mg | Inquiry | $ 787.00 |
Description | Shepherdin is a synthetic peptide mirroring amino acids 79-87 of human survivin, acting as an inhibitor of the survivin-heat shock protein 90 (Hsp90) interaction. It specifically targets the N-terminal domain of Hsp90, blocking the survivin-Hsp90 interaction in human reticulocyte extracts at a 150 µM concentration. Conjugates of Shepherdin with cell-permeable peptides, such as penetratin or the HIV Tat sequence, exhibit anticancer properties both in vitro and in vivo. |
Synonyms | Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu-OH, Survivin (79-87) |
Molecular Weight | 949.10 |
Formula | C41H64N12O12S.XCF3COOH |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
Methanol: Soluble
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Shepherdin TFA Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu-OH Survivin (79-87) inhibitor inhibit