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Anti-MZB1/PERP1 Antibody (1A338) is a Rabbit antibody targeting MZB1/PERP1. Anti-MZB1/PERP1 Antibody (1A338) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-MZB1/PERP1 Antibody (1A338) is a Rabbit antibody targeting MZB1/PERP1. Anti-MZB1/PERP1 Antibody (1A338) can be used in IHC-P. |
Alias | pERp1, PACAP, MEDA-7, marginal zone B and B1 cell-specific protein, HSPC190 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1A338 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human MGC29506 in human spleen with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human MGC29506 in human small intestine with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:250-1:1000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PERP1 / MZB1 (rh PERP1 / MZB1; TMPY-03630; Q8WU39-1; Met 1- Thr 185). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of gastric cancer (GC). Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human PERP1 / MZB1 Protein (TMPY-03630) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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