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Protein S/PROS1 Protein, Human, Recombinant (His)

(Synonyms: THPH6, THPH5, PSA, PS25, PS24, PS23, PS22, PS21, protein S (α), protein S (alpha), Protein S, PROS) Copy Product Info

Synonyms: THPH6, THPH5, PSA, PS25, PS24, PS23, PS22, PS21, protein S (α), protein S (alpha), Protein S, PROS

Catalog No. TMPY-03848 Copy Product Info
Purity: 96.9%
Protein S/PROS1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 74.1 kDa and the accession number is P07225.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$70-In Stock
10 µg$109-In Stock
20 µg$182-In Stock
50 µg$357-In Stock
100 µg$600-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.9%
Appearance:Lyophilized powder
Color:White
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Product Information

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Protein S/PROS1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 74.1 kDa and the accession number is P07225.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP07225
ConstructionA DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Asn 25
Protein Purity
> 95 % as determined by SDS-PAGE
Protein S/PROS1 Protein, Human, Recombinant (His)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
SynonymsTHPH6, THPH5, PSA, PS25, PS24, PS23, PS22, PS21, protein S (α), protein S (alpha), Protein S, PROS
Research Background
PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.
Chemical Properties
Molecular Weight74.1 kDa (predicted); 69-89 kDa (reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: Protein S/PROS1 Protein, Human, Recombinant (His) chemical structure | Protein S/PROS1 Protein, Human, Recombinant (His) molecular weight