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Anti-CCR3 Polyclonal Antibody is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-CCR3 Polyclonal Antibody is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
Alias | Probable C-C chemokine receptor type 3, MIP-1 alpha RL2, MIP1 alpha RL2, MIP-1 alpha receptor like-2, MGC102841, Macrophage inflammatory protein 1-alpha receptor-like 2, Macrophage inflammatory protein 1 alpha receptor like 2, Eotaxin receptor, Eosinophil eotaxin receptor, Eosinophil CC chemokine receptor 3, CMKBR3, CMKBR1L2, CMKBR 3, CMKB R3, CKR3, CKR 3, CK R3, Chemokine(CC) receptor 1 like 2, Chemokine(C-C motif) receptor 3, Chemokine receptor 3, Chemokine CC motif receptor 3, CD193 antigen, CD193, CD 193, CCR-3, CCR3, CCR 3, CC-CKR-3, CCCKR3, CC R3, C-C CKR-3, CC CKR 3, C-C chemokine receptor type 3, CC chemokine receptor type 3, CC chemokine receptor 3, C C CKR 3, B chemokine receptor |
Ig Type | IgG |
Reactivity | Human,Rat (predicted:Mouse,Dog,Cow) |
Verified Activity | 1. Tissue/cell: rat colitis tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-CCR3 Polyclonal Antibody, Unconjugated (TMAB-00324) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Tissue/cell: human breast carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-CCR3 Polyclonal Antibody, Unconjugated (TMAB-00324) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
Application | IHC-P,IHC-Fr,IF |
Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described. |
Immunogen | KLH conjugated synthetic peptide: human CCR3 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | HIV-related,Beta Chemokine Rec. (CCR),GPCR |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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