sST2 Protein, Human, Recombinant

Name: sST2 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-07207
Rating: 4.5 (1 reviews)

(Synonyms: T1, ST2V, ST2L, ST2, IL33R, FIT-1, DER4) Copy Product Info

Synonyms: T1, ST2V, ST2L, ST2, IL33R, FIT-1, DER4

Catalog No. TMPY-07207 Copy Product Info

sST2 Protein, Human, Recombinant is expressed in E. coli.

Pack Size	Price	USA Stock	Global Stock	Quantity
250 µg	Inquiry	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	sST2 Protein, Human, Recombinant is expressed in E. coli.
Species	Human
Expression System	E. coli
Protein Purity	≥ 90% as determined by SDS-PAGE.
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 4 M Urea, 10% Glycerol, pH 7.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	T1, ST2V, ST2L, ST2, IL33R, FIT-1, DER4
Research Background	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.

Chemical Properties

Molecular Weight

35.82 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.