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Polygalic acid

Name: Polygalic acid
Brand: TargetMol
SKU: T3S2197
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3S2197Cas No. 1260-04-4

Alias Senegenic acid

Polygalic acid (Senegenic acid), a triterpenoid saponin, is a major active ingredient in Polygala tenuifolia. Polygalic acid shows expectorant, emetic and stimulant effects.

Polygalic acid

🥰Excellent

Purity: 99.52%

Catalog No. T3S2197Alias Senegenic acidCas No. 1260-04-4

Polygalic acid (Senegenic acid), a triterpenoid saponin, is a major active ingredient in Polygala tenuifolia. Polygalic acid shows expectorant, emetic and stimulant effects.

Pack Size	Price	Availability
5 mg	$37	In Stock
10 mg	$64	In Stock
25 mg	$113	In Stock
50 mg	$163	In Stock
100 mg	$239	In Stock
200 mg	$367	In Stock
1 mL x 10 mM (in DMSO)	$51	In Stock

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Batch Information

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Purity:99.52%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Polygalic acid (Senegenic acid), a triterpenoid saponin, is a major active ingredient in Polygala tenuifolia. Polygalic acid shows expectorant, emetic and stimulant effects.
Synonyms	Senegenic acid

Chemical Properties

Molecular Weight	488.66
Formula	C₂₉H₄₄O₆
Cas No.	1260-04-4
Smiles	[H][C@@]12CC(C)(C)CC[C@]1(CCC1=C2CC[C@@]2([H])[C@@]1(C)CC[C@@]1([H])[C@@](C)([C@@H](O)[C@@H](O)C[C@]21C)C(O)=O)C(O)=O
Relative Density.	1.25 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 89 mg/mL (182.13 mM), Sonication is recommended.

Pyridine, Methanol, etc.: Soluble

Ethanol: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0464 mL	10.2321 mL	20.4641 mL	102.3206 mL
5 mM	0.4093 mL	2.0464 mL	4.0928 mL	20.4641 mL
10 mM	0.2046 mL	1.0232 mL	2.0464 mL	10.2321 mL
20 mM	0.1023 mL	0.5116 mL	1.0232 mL	5.1160 mL
50 mM	0.0409 mL	0.2046 mL	0.4093 mL	2.0464 mL
100 mM	0.0205 mL	0.1023 mL	0.2046 mL	1.0232 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc