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S100A1 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P23297.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 μg | $353 | 7-10 days | |
25 μg | $833 | 7-10 days | |
50 μg | $1,080 | 7-10 days |
Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
Description | S100A1 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P23297. |
Species | Human |
Expression System | E. coli |
Tag | His |
Accession Number | P23297 |
Synonyms | S100-alpha,S100-A1,S100A1,S100A,S-100 protein alpha subunit,S-100 protein alpha chain,S100 calcium-binding protein A1,S100,Protein S100-A1 |
Construction | Met1-Ser94 |
Protein Purity | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
Molecular Weight | ~11.5 kDa (Reducing conditions) |
Endotoxin | < 1 EU/μg of protein as determined by the LAL method. |
Formulation | Lyophilized after extensive dialysis against 20 mM Tris-HCl, 0.1 mM EDTA, pH 7.0. |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O at 200 μg/ml. |
Stability & Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | S100 calcium-binding protein A1 (S100A1) is a small calcium binding protein with EF-hand structures and belongs to the S100 family. S100 proteins include at least 25 members which are located as a cluster on human chromosome 1q21. S100A1 is found in the heart, skeletal muscle, brain, and kidney.S100A1 mainly resides on the sarcoplasmic reticulum, mitochondria and myofilaments. S100A1 may function in stimulation of Ca 2+ induced Ca 2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. |
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