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Anti-EpCAM/TROP1 Antibody (1A804)
😃Good
Catalog No. TMAY-03372
Alias TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5
Anti-EpCAM/TROP1 Antibody (1A804) is a Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (1A804) can be used in WB,ELISA,ELISA(Det),IHC-P.
Anti-EpCAM/TROP1 Antibody (1A804)
Anti-EpCAM/TROP1 Antibody (1A804)
😃Good
Catalog No. TMAY-03372Alias TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5
Anti-EpCAM/TROP1 Antibody (1A804) is a Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (1A804) can be used in WB,ELISA,ELISA(Det),IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $94 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: WB, ELISA, ELISA(Det), IHC-P Reactivity: Mouse |
| Alias | TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5 |
| Ig Type | Rabbit IgG |
| Clone | 1A804 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunochemical staining of mouse EpCAM in mouse uterus with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of mouse EpCAM in mouse stomach with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. 3. Immunochemical staining of mouse EpCAM in mouse intestine with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. 4. Anti-EPCAM rabbit monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:35 kDa. -Observed band size:38 kDa |
| Application | WB,ELISA,ELISA(Det),IHC-P |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:25000-1:50000; IHC-P: 1:500-1:2000; ELISA(Det): 1:5000-1:50000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse EpCAM / TROP-1 / TACSTD1 (rM EpCAM / TROP-1 / TACSTD1; TMPY-01766; NP_032558.2; Met 1-Thr 266). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse EpCAM / TROP-1 / TACSTD1 protein (TMPY-01766) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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