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TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $58 | 7-10 days | |
| 10 μg | $92 | 7-10 days | |
| 20 μg | $148 | 7-10 days | |
| 50 μg | $289 | 7-10 days | |
| 100 μg | $487 | In Stock | |
| 200 μg | $883 | 7-10 days | |
| 500 μg | $1,950 | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis. |
| Species | Cynomolgus |
| Expression System | E. coli |
| Tag | N-His |
| Accession Number | XP_005590891.2 |
| Synonyms | Tryptase-1,Tryptase α-1,Tryptase α/β-1,Tryptase I,Tryptase alpha-1,Tryptase alpha/beta-1,TPSB1,TPS2,TPS1 |
| Construction | Ile38-Pro282 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Molecular Weight | 28.57kDa (predicted). The protein migrates to 30-33kDa based on Tris-Bis PAGE result. |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 250 mM NaCl, 2 mM CaCl2, 10% Glycerol (pH 8.0). |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis. |

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