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TPSAB1 protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-01303
Synonyms: Tryptase alpha/beta-1, TPSB1, Tryptase I, TPS2, TPS1, Tryptase alpha-1, Tryptase-1, Tryptase α/β-1, Tryptase α-1

TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin­like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.

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TPSAB1 protein, Cynomolgus, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 487.00
500 μg 5 days $ 1,950.00
1 mg 5 days $ 3,250.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin­like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
Species Cynomolgus
Expression System E. coli
Tag N-His
Accession Number XP_005590891.2
Synonyms Tryptase alpha/beta-1, TPSB1, Tryptase I, TPS2, TPS1, Tryptase alpha-1, Tryptase-1, Tryptase α/β-1, Tryptase α-1
Construction Recombinant Cynomolgus TPSAB1 protein is expressed fromE.coliwith His tag at the N-Terminus. It contains Ile38-Pro282.[Accession |XP_005590891.2]
Protein Purity > 95% as determined by Tris-Bis PAGE
Molecular Weight The protein has a predicted MW of 28.57kDa. The protein migrates to 30-33kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Supplied as 0.22μm filtered solution in 20mM Tris, 250mM NaCl, 2mM CaCl2, 10% Glycerol (pH 8.0).
Stability & Storage

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin­like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.

References and Literature

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Keywords

TPSAB1 protein, Cynomolgus, Recombinant (His) Tryptase a/b-1 Tryptase alpha/beta-1 TPSB1 Tryptase I TPS2 TPSB 1 TPS1 TPS 1 Tryptase alpha-1 TPS 2 Tryptase-1 TPSB-1 Tryptase α/β-1 TPS-1 Tryptase α-1 TPS-2 Tryptase a-1 recombinant recombinant-proteins proteins protein

 

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