TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 487.00 | |
500 μg | 5 days | $ 1,950.00 | |
1 mg | 5 days | $ 3,250.00 |
Description | TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis. |
Species | Cynomolgus |
Expression System | E. coli |
Tag | N-His |
Accession Number | XP_005590891.2 |
Synonyms | Tryptase alpha/beta-1, TPSB1, Tryptase I, TPS2, TPS1, Tryptase alpha-1, Tryptase-1, Tryptase α/β-1, Tryptase α-1 |
Construction | Recombinant Cynomolgus TPSAB1 protein is expressed fromE.coliwith His tag at the N-Terminus. It contains Ile38-Pro282.[Accession |XP_005590891.2] |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | The protein has a predicted MW of 28.57kDa. The protein migrates to 30-33kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22μm filtered solution in 20mM Tris, 250mM NaCl, 2mM CaCl2, 10% Glycerol (pH 8.0). |
Stability & Storage |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis. |
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Please read the User Guide of Recombinant Proteins for more specific information.
TPSAB1 protein, Cynomolgus, Recombinant (His) Tryptase a/b-1 Tryptase alpha/beta-1 TPSB1 Tryptase I TPS2 TPSB 1 TPS1 TPS 1 Tryptase alpha-1 TPS 2 Tryptase-1 TPSB-1 Tryptase α/β-1 TPS-1 Tryptase α-1 TPS-2 Tryptase a-1 recombinant recombinant-proteins proteins protein