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Anti-FGFBP1 Polyclonal Antibody

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Catalog No. TMAB-00673
Alias HBP17, Fibroblast growth factor binding protein 1 precursor, FGFP1, FGFBP1, FGFBP, FGF-binding protein, FGF BP1, FGF BP, FGF binding protein 1, 17 kDa heparin binding growth factor binding protein

Anti-FGFBP1 Polyclonal Antibody is a Rabbit antibody targeting FGFBP1. Anti-FGFBP1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.

Anti-FGFBP1 Polyclonal Antibody

Anti-FGFBP1 Polyclonal Antibody

😃Good
Catalog No. TMAB-00673Alias HBP17, Fibroblast growth factor binding protein 1 precursor, FGFP1, FGFBP1, FGFBP, FGF-binding protein, FGF BP1, FGF BP, FGF binding protein 1, 17 kDa heparin binding growth factor binding protein
Anti-FGFBP1 Polyclonal Antibody is a Rabbit antibody targeting FGFBP1. Anti-FGFBP1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3737-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-FGFBP1 Polyclonal Antibody is a Rabbit antibody targeting FGFBP1. Anti-FGFBP1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
SynonymsHBP17, Fibroblast growth factor binding protein 1 precursor, FGFP1, FGFBP1, FGFBP, FGF-binding protein, FGF BP1, FGF BP, FGF binding protein 1, 17 kDa heparin binding growth factor binding protein
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat)
Verified Activity
1. Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-FGFBP1 Polyclonal Antibody, Unconjugated (TMAB-00673) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Tissue/cell: mouse stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-FGFBP1 Polyclonal Antibody, Unconjugated (TMAB-00673) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
3. Paraformaldehyde-fixed, paraffin embedded (human skin cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (FGFBP1) Polyclonal Antibody, Unconjugated (TMAB-00673) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
Anti-FGFBP1 Polyclonal AntibodyAnti-FGFBP1 Polyclonal AntibodyAnti-FGFBP1 Polyclonal Antibody
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space. Cell membrane; Peripheral membrane protein. Note=Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.
Tissue SpecificityExpressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carc
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FGFBP
Antigen Species
Human
Gene Name
FGFBP1
Gene ID
Protein Name
Fibroblast growth factor-binding protein 1
Uniprot ID
Biology Area
FGF,FGF,FGF
Function
Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.
Chemical Properties
Molecular WeightTheoretical: 23 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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