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Orphenadrine hydrochloride

Name: Orphenadrine hydrochloride
Brand: TargetMol
SKU: T1308
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1308Cas No. 341-69-5

Alias Mephenamin, Mebedrol

Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

Orphenadrine hydrochloride

🥰Excellent

Purity: 99.88%

Catalog No. T1308Alias Mephenamin, MebedrolCas No. 341-69-5

Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

Pack Size	Price	Availability
10 mg	$30	In Stock
50 mg	$39	In Stock
100 mg	$46	In Stock
200 mg	$84	In Stock
500 mg	$136	In Stock
1 g	$196	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Batch Information

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Purity:99.88%

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COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Targets&IC50	NMDAR:6.0 ±0.7 μM (Ki)
Synonyms	Mephenamin, Mebedrol

Chemical Properties

Molecular Weight	305.85
Formula	C₁₈H₂₃NO·HCl
Cas No.	341-69-5
Smiles	Cl.CN(C)CCOC(c1ccccc1)c1ccccc1C
Relative Density.	1.014g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (147.13 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2696 mL	16.3479 mL	32.6958 mL	163.4788 mL
5 mM	0.6539 mL	3.2696 mL	6.5392 mL	32.6958 mL
10 mM	0.3270 mL	1.6348 mL	3.2696 mL	16.3479 mL
20 mM	0.1635 mL	0.8174 mL	1.6348 mL	8.1739 mL
50 mM	0.0654 mL	0.3270 mL	0.6539 mL	3.2696 mL
100 mM	0.0327 mL	0.1635 mL	0.3270 mL	1.6348 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc