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Poly(hexamethylenebiguanide) hydrochloride

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Catalog No. T77210Cas No. 32289-58-0
Alias Polyhexamethylene biguanide hydrochloride, PHMB

Poly(hexamethylenebiguanide) hydrochloride, serving as an antimicrobial agent, finds applications across various fields including medical, apparel, and household textiles [1].

Poly(hexamethylenebiguanide) hydrochloride

Poly(hexamethylenebiguanide) hydrochloride

😃Good
Catalog No. T77210Alias Polyhexamethylene biguanide hydrochloride, PHMBCas No. 32289-58-0
Poly(hexamethylenebiguanide) hydrochloride, serving as an antimicrobial agent, finds applications across various fields including medical, apparel, and household textiles [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 g$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Poly(hexamethylenebiguanide) hydrochloride, serving as an antimicrobial agent, finds applications across various fields including medical, apparel, and household textiles [1].
SynonymsPolyhexamethylene biguanide hydrochloride, PHMB
Chemical Properties
Molecular Weight249.79
Formula(C8H17N5)n.xHCl
Cas No.32289-58-0
SmilesCl.CNC(=N)NCCCCCCNC(C)=N
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80.00 mg/mL (320.27 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.30 mg/mL (13.21 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0034 mL20.0168 mL40.0336 mL200.1681 mL
5 mM0.8007 mL4.0034 mL8.0067 mL40.0336 mL
10 mM0.4003 mL2.0017 mL4.0034 mL20.0168 mL
20 mM0.2002 mL1.0008 mL2.0017 mL10.0084 mL
50 mM0.0801 mL0.4003 mL0.8007 mL4.0034 mL
100 mM0.0400 mL0.2002 mL0.4003 mL2.0017 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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