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Anti-Irisin Polyclonal Antibody (Synonyms: Irisin, FNDC5, Fibronectin type III repeat-containing protein 2, F...)

Catalog No. TMAB-00987 Copy Product Info
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Anti-Irisin Polyclonal Antibody is a Rabbit antibody targeting Irisin. Anti-Irisin Polyclonal Antibody can be used in WB.

Anti-Irisin Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-00987
Synonyms Irisin, FNDC5, Fibronectin type III repeat-containing protein 2, Fibronectin type III domain-containing protein 5

Anti-Irisin Polyclonal Antibody is a Rabbit antibody targeting Irisin. Anti-Irisin Polyclonal Antibody can be used in WB.

Anti-Irisin Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Irisin Polyclonal Antibody is a Rabbit antibody targeting Irisin. Anti-Irisin Polyclonal Antibody can be used in WB.
SynonymsIrisin, FNDC5, Fibronectin type III repeat-containing protein 2, Fibronectin type III domain-containing protein 5
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Chicken,Dog,Rabbit)
Verified Activity
Sample:
HepG2 (Human) Cell Lysate at 30 μg
NIH/3T3 (Mouse) Cell Lysate at 30 μg
K562 (Human) Lysate at 30 μg
Heart (Mouse) Lysate at 40 μg
Primary: Anti-FNDC5 (TMAB-00987) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 12/20 kDa
Observed band size: 20 kDa
verifiedActivity
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway.Irisin: Secreted. Note=Detected in the blood of individuals subjected to endurance exercise.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FNDC5
Antigen Species
Human
Gene Name
FNDC5
Gene ID
Protein Name
Fibronectin type III domain-containing protein 5
Uniprot ID
Biology Area
Other Antibodies,Obesity
Function
Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.
Chemical Properties
Molecular WeightTheoretical: 12/20 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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