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Anti-Irisin Polyclonal Antibody
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Catalog No. TMAB-00987
Alias Irisin, FNDC5, Fibronectin type III repeat-containing protein 2, Fibronectin type III domain-containing protein 5
Anti-Irisin Polyclonal Antibody is a Rabbit antibody targeting Irisin. Anti-Irisin Polyclonal Antibody can be used in WB.
Anti-Irisin Polyclonal Antibody
Anti-Irisin Polyclonal Antibody
😃Good
Catalog No. TMAB-00987Alias Irisin, FNDC5, Fibronectin type III repeat-containing protein 2, Fibronectin type III domain-containing protein 5
Anti-Irisin Polyclonal Antibody is a Rabbit antibody targeting Irisin. Anti-Irisin Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Irisin Polyclonal Antibody is a Rabbit antibody targeting Irisin. Anti-Irisin Polyclonal Antibody can be used in WB. |
| Synonyms | Irisin, FNDC5, Fibronectin type III repeat-containing protein 2, Fibronectin type III domain-containing protein 5 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Rabbit) |
| Verified Activity | Sample: HepG2 (Human) Cell Lysate at 30 μg NIH/3T3 (Mouse) Cell Lysate at 30 μg K562 (Human) Lysate at 30 μg Heart (Mouse) Lysate at 40 μg Primary: Anti-FNDC5 (TMAB-00987) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12/20 kDa Observed band size: 20 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway.Irisin: Secreted. Note=Detected in the blood of individuals subjected to endurance exercise. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]. |
| Immunogen | KLH conjugated synthetic peptide: human FNDC5 |
| Antigen Species | Human |
| Gene Name | FNDC5 |
| Gene ID | |
| Protein Name | Fibronectin type III domain-containing protein 5 |
| Uniprot ID | |
| Biology Area | Other Antibodies,Obesity |
| Function | Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. |
| Molecular Weight | Theoretical: 12/20 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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