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BDNF Protein, Human/Murine/Rat, Recombinant
(Synonyms: Brain-Derived Neurotrophic Factor, BDNF, Abrineurin) Copy Product InfoSynonyms: Brain-Derived Neurotrophic Factor, BDNF, Abrineurin
Catalog No. TMPJ-00135 Copy Product Info
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $96 | - | In Stock | |
| 10 μg | $157 | In Stock | In Stock | |
| 20 μg | $258 | 7-10 days | 7-10 days | |
| 50 μg | $513 | 7-10 days | 7-10 days | |
| 100 μg | $759 | 7-10 days | 7-10 days | |
| 200 μg | $1,120 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease. |
| Species | Human,Mouse,Rat |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P23560 |
| Amino Acid | His129-Arg247 |
| Construction | His129-Arg247 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) https://cdn.targetmol.com/group3/M00/13/60/CgoaEWZG0uSEIuzdAAAAAB5fZvE289.png |
| Endotoxin | < 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 250 mM NaCl, pH 7.2. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Brain-Derived Neurotrophic Factor, BDNF, Abrineurin |
| Research Background |
| Molecular Weight | 14 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: BDNF Protein, Human/Murine/Rat, Recombinant chemical structure | BDNF Protein, Human/Murine/Rat, Recombinant molecular weight
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