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MMP-9-IN-7

🥰Excellent
Catalog No. T72069Cas No. 333746-76-2

Acetamide, N-[2-[(5-chloro-2 methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]-inhibits pro-matrix metalloproteinase activation and can be used to prevent, treat or ameliorate MMP9 and/or MMP13-mediated syndromes.

MMP-9-IN-7

MMP-9-IN-7

🥰Excellent
Purity: 97.65%
Catalog No. T72069Cas No. 333746-76-2
Acetamide, N-[2-[(5-chloro-2 methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]-inhibits pro-matrix metalloproteinase activation and can be used to prevent, treat or ameliorate MMP9 and/or MMP13-mediated syndromes.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$58-In Stock
5 mg$133-In Stock
10 mg$198-In Stock
25 mg$343-In Stock
50 mg$513-In Stock
100 mg$746-In Stock
500 mg$1,560-In Stock
1 mL x 10 mM (in DMSO)$133-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.65%
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Product Introduction

Bioactivity
Description
Acetamide, N-[2-[(5-chloro-2 methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]-inhibits pro-matrix metalloproteinase activation and can be used to prevent, treat or ameliorate MMP9 and/or MMP13-mediated syndromes.
Targets&IC50
TAOK2:1.1 µM, MMP9:0.52 μM
Chemical Properties
Molecular Weight394.9
FormulaC16H15ClN4O2S2
Cas No.333746-76-2
SmilesCC1=C(C=2N=C(NC3=C(OC)C=CC(Cl)=C3)SC2)SC(NC(C)=O)=N1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (126.61 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5323 mL12.6614 mL25.3229 mL126.6143 mL
5 mM0.5065 mL2.5323 mL5.0646 mL25.3229 mL
10 mM0.2532 mL1.2661 mL2.5323 mL12.6614 mL
20 mM0.1266 mL0.6331 mL1.2661 mL6.3307 mL
50 mM0.0506 mL0.2532 mL0.5065 mL2.5323 mL
100 mM0.0253 mL0.1266 mL0.2532 mL1.2661 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

MMP-9MMP-13
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