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Quipazine dimaleate

Name: Quipazine dimaleate
Brand: TargetMol
SKU: T23212
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23212Cas No. 150323-78-7

Quipazine dimaleate is a selective 5-HT3 agonist.

Quipazine dimaleate

🥰Excellent

Purity: 99.91%

Catalog No. T23212Cas No. 150323-78-7

Quipazine dimaleate is a selective 5-HT3 agonist.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$30	In Stock	In Stock
25 mg	$44	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.91%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Quipazine dimaleate is a selective 5-HT3 agonist.
In vivo	Quipazine dimaleate dose-dependently reduces aggressive dominance in testosterone propionate-dominant rats, as well as in naturally dominant rats. When the serotonergic antagonists pirenpirone or pizotyline are coadministered with Quipazine dimaleate to either group of dominant rats, they blocks the effect of Quipazine dimaleate in reducing dominance[1].

Chemical Properties

Molecular Weight	445.42
Formula	C₂₁H₂₃N₃O₈
Cas No.	150323-78-7
Smiles	OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C1CN(CCN1)c1ccc2ccccc2n1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 29.7 mg/mL (66.68 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.2451 mL	11.2254 mL	22.4507 mL	112.2536 mL
5 mM	0.4490 mL	2.2451 mL	4.4901 mL	22.4507 mL
10 mM	0.2245 mL	1.1225 mL	2.2451 mL	11.2254 mL
20 mM	0.1123 mL	0.5613 mL	1.1225 mL	5.6127 mL
50 mM	0.0449 mL	0.2245 mL	0.4490 mL	2.2451 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc