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7-Oxo-beta-sitosterol
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Catalog No. TN3248Cas No. 2034-74-4
Alias 7-Oxo-β-sitosterol, 7-Ketositosterol
7-Oxo-beta-sitosterol (7-Ketositosterol), a phytosterol isolated from the fruit of x giganteus, has anticancer and antitumor activity, inhibits the proliferation of HL-60 acute myeloid leukemia (AML) cells, and stimulates the growth of HL-60 acute myeloid leukemia (AML) cells through the downregulation of the levels of S1P, p-44/42 ERK1/2 and p-NF-κB p65 proteins. -κB p65 protein levels to stimulate ceramide accumulation and apoptosis, and can be used to study breast cancer.
7-Oxo-beta-sitosterol
😃Good
Catalog No. TN3248Alias 7-Oxo-β-sitosterol, 7-KetositosterolCas No. 2034-74-4
7-Oxo-beta-sitosterol (7-Ketositosterol), a phytosterol isolated from the fruit of x giganteus, has anticancer and antitumor activity, inhibits the proliferation of HL-60 acute myeloid leukemia (AML) cells, and stimulates the growth of HL-60 acute myeloid leukemia (AML) cells through the downregulation of the levels of S1P, p-44/42 ERK1/2 and p-NF-κB p65 proteins. -κB p65 protein levels to stimulate ceramide accumulation and apoptosis, and can be used to study breast cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $120 | In Stock | |
| 10 mg | $229 | In Stock | |
| 25 mg | $533 | 35 days | |
| 50 mg | $949 | 35 days |
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Chemical Properties
| Description | 7-Oxo-beta-sitosterol (7-Ketositosterol), a phytosterol isolated from the fruit of x giganteus, has anticancer and antitumor activity, inhibits the proliferation of HL-60 acute myeloid leukemia (AML) cells, and stimulates the growth of HL-60 acute myeloid leukemia (AML) cells through the downregulation of the levels of S1P, p-44/42 ERK1/2 and p-NF-κB p65 proteins. -κB p65 protein levels to stimulate ceramide accumulation and apoptosis, and can be used to study breast cancer. |
| Synonyms | 7-Oxo-β-sitosterol, 7-Ketositosterol |
| Molecular Weight | 428.69 |
| Formula | C29H48O2 |
| Cas No. | 2034-74-4 |
| Smiles | C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3=O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@H](C(C)C)CC)C)[H])[H] |
| Relative Density. | 1.01 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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