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ASGR2 Protein, Human, Recombinant (His)
(Synonyms: HL-2, HBXBP, CLEC4H2, asialoglycoprotein receptor 2, ASGP-R2, ASGPR2) Copy Product InfoSynonyms: HL-2, HBXBP, CLEC4H2, asialoglycoprotein receptor 2, ASGP-R2, ASGPR2
Catalog No. TMPY-02909 Copy Product Info
ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $93 | 7-10 days | 7-10 days | |
| 10 μg | $152 | 7-10 days | 7-10 days | |
| 20 μg | $248 | 7-10 days | 7-10 days | |
| 50 μg | $498 | 7-10 days | 7-10 days | |
| 100 μg | $857 | 7-10 days | 7-10 days | |
| 200 μg | $1,460 | 7-10 days | 7-10 days | |
| 500 μg | $2,930 | 7-10 days | 7-10 days | |
| 1 mg | $5,930 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-His |
| Accession Number | P07307-1 |
| Construction | A DNA sequence encoding the human ASGR2 (P07307-1) (Gln80-Ala311) was expressed, with an N-terminal polyhistidine tag. Predicted N terminal: His |
| Protein Purity | > 95 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | HL-2, HBXBP, CLEC4H2, asialoglycoprotein receptor 2, ASGP-R2, ASGPR2 |
| Research Background |
| Molecular Weight | 28.9 kDa (predicted); 37-42 kDa (reducing condition, due to glycosylation) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: ASGR2 Protein, Human, Recombinant (His) chemical structure | ASGR2 Protein, Human, Recombinant (His) molecular weight
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