ATG3 Protein, Human, Recombinant

Name: ATG3 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-01354
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Ubiquitin-like-conjugating enzyme ATG3, Protein PC3-96, hApg3, Autophagy-related protein 3, ATG3, APG3-like, APG3L, APG3) Copy Product Info

Synonyms: Ubiquitin-like-conjugating enzyme ATG3, Protein PC3-96, hApg3, Autophagy-related protein 3, ATG3, APG3-like, APG3L, APG3

Catalog No. TMPJ-01354 Copy Product Info

Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$35	-	In Stock
20 µg	$53	-	In Stock
50 µg	$97	-	In Stock
100 µg	$148	-	In Stock
200 µg	$236	7-10 days	7-10 days
500 µg	$433	7-10 days	7-10 days
1 mg	$621	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Solution

Color:Transparent

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.
Species	Human
Expression System	E. coli
Tag	C-6xHis, N-T7
Accession Number	Q9NT62
Amino Acid	Met1-Met314
Construction	Met1-Met314
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.0.
Synonyms	Ubiquitin-like-conjugating enzyme ATG3, Protein PC3-96, hApg3, Autophagy-related protein 3, ATG3, APG3-like, APG3L, APG3
Research Background	Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

Chemical Properties

Molecular Weight

38 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.