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Anti-LDLR Antibody-PE (3N325)
🥰Excellent
Catalog No. TMAY-03221P
Anti-LDLR Antibody-PE (3N325) is a PE-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-PE (3N325) can be used in FCM.
Anti-LDLR Antibody-PE (3N325)
Anti-LDLR Antibody-PE (3N325)
🥰Excellent
Catalog No. TMAY-03221P
Anti-LDLR Antibody-PE (3N325) is a PE-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-PE (3N325) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-LDLR Antibody-PE (3N325) is a PE-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-PE (3N325) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3N325 |
| Reactivity | Mouse |
| Verified Activity | Profile of anti-LDLR reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 prior to staining, washed, then stained with PE Rabbit anti-LDLR. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LDLR / LDL Receptor (rM LDLR / LDL Receptor; TMPY-01014; NP_034830.2; Met 1-Arg 790) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low-density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants. |
| Conjucates | PE |
| Others Formats | Unconjugated/PerCP/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse LDLR / LDL Receptor protein (TMPY-01014) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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