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TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
(Synonyms: tβR-I, TGFβRI, TGF-β RI, TGFR-1, TGF-bRI, TGFBR1, TGFbetaRI, TGF-beta RI, TGFB1R1, tbetaR-I, SKR4, LDS2A, LDS1A, ALK-5, ACVRLK4, AAT5) Copy Product InfoSynonyms: tβR-I, TGFβRI, TGF-β RI, TGFR-1, TGF-bRI, TGFBR1, TGFbetaRI, TGF-beta RI, TGFB1R1, tbetaR-I, SKR4, LDS2A, LDS1A, ALK-5, ACVRLK4, AAT5
Catalog No. TMPK-00306 Copy Product Info
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $91 | - | In Stock | |
| 10 μg | $148 | - | In Stock | |
| 20 μg | $245 | - | In Stock | |
| 50 μg | $483 | - | In Stock | |
| 100 μg | $813 | 7-10 days | 7-10 days | |
| 200 μg | $1,470 | 7-10 days | 7-10 days | |
| 500 μg | $3,250 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-mFc-Avi |
| Accession Number | P36897-1 |
| Construction | Leu34-Glu125 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | tβR-I, TGFβRI, TGF-β RI, TGFR-1, TGF-bRI, TGFBR1, TGFbetaRI, TGF-beta RI, TGFB1R1, tbetaR-I, SKR4, LDS2A, LDS1A, ALK-5, ACVRLK4, AAT5 |
| Research Background |
| Molecular Weight | 38.2 kDa (predicted). Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result. |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated chemical structure | TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated molecular weight
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