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KIR3DL3 Protein, Human, Recombinant (His)

Catalog No. TMPY-00217
Synonyms: KIR44, KIR3DL7, CD158Z, KIRC1, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3, KIR2DS2

KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the Immunoglobulin domains and the transmembrane region. KIR3DL3 gene is not a pseudogene but encodes a protein that is not expressed in healthy individuals. Protein expression might be induced under certain developmental or pathological situations.

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KIR3DL3 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg In stock $ 451.00
200 μg 5 days $ 798.00
500 μg 5 days $ 1,690.00
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Biological Description
Technical Params
Product Properties
Biological Information Testing in progress
Description KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the Immunoglobulin domains and the transmembrane region. KIR3DL3 gene is not a pseudogene but encodes a protein that is not expressed in healthy individuals. Protein expression might be induced under certain developmental or pathological situations.
Species Human
Expression System HEK293
Tag His
Accession Number Q8N743
Synonyms KIR44, KIR3DL7, CD158Z, KIRC1, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3, KIR2DS2
Construction A DNA sequence encoding the human KIR3DL3 (NP_703144.2) (Met1-Leu322) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE

Molecular Weight 33.7 kDa (predicted)
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the Immunoglobulin domains and the transmembrane region. KIR3DL3 gene is not a pseudogene but encodes a protein that is not expressed in healthy individuals. Protein expression might be induced under certain developmental or pathological situations.

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Keywords

KIR3DL3 Protein, Human, Recombinant (His) KIR44 KIR3DL7 KIR-44 CD158Z KIRC1 KIR 44 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 KIR2DS2 KIRC-1 KIRC 1 recombinant recombinant-proteins proteins protein

 

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