At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | In stock | $ 38.00 | |
50 μg | 5 days | $ 110.00 | |
500 μg | 5 days | $ 306.00 | |
1 mg | 5 days | $ 682.00 |
Biological Information |
Loaded Human IFNAR2-Fc on Protein A Biosensor, can bind Human IFN alpha2a with an affinity constant of 1.95 nM as determined in BLI assay. (Regularly tested)
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Description | At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end. |
Species | Human |
Expression System | E. coli |
Tag | None |
Accession Number | P01563 |
Synonyms | Interferon α-2, IFNA2, IFN α2a, IFN-α-2, IFN-Alpha-2, Interferon Alpha-2, LeIF A, Interferon α-A, Interferon Alpha-A |
Amino Acid | Cys24-Glu188(Arg46Lys) |
Construction | Recombinant Human Interferon Alpha-2a is produced by our E.coli expression system and the target gene encoding Cys24-Glu188(Arg46Lys) is expressed. |
Protein Purity |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
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Molecular Weight | 16 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end. |
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Please read the User Guide of Recombinant Proteins for more specific information.
IFN-alpha 2a/IFNA2 Protein, Human, Recombinant Interferon α-2 IFNA2 IFN-a-2 Interferon a-A IFNA 2 Interferon a-2 IFN α2a IFN-α-2 IFN-Alpha-2 IFNA-2 Interferon Alpha-2 LeIF A Interferon α-A Interferon Alpha-A recombinant recombinant-proteins proteins protein