FKBP4 Protein, Human, Recombinant (His)

Name: FKBP4 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01076
Rating: 4.5 (1 reviews)

(Synonyms: Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP4, immunophilin FKBP52, HSP-binding immunophilin, FKBP59, FKBP4, FK506-binding protein 4, 59kDa immunophilin, 51kDa FK506-binding protein) Copy Product Info

Synonyms: Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP4, immunophilin FKBP52, HSP-binding immunophilin, FKBP59, FKBP4, FK506-binding protein 4, 59kDa immunophilin, 51kDa FK506-binding protein

Catalog No. TMPJ-01076 Copy Product Info

FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.

Pack Size	Price	USA Stock	Global Stock
10 µg	$53	7-10 days	7-10 days
20 µg	$77	7-10 days	7-10 days
50 µg	$129	7-10 days	7-10 days
1 mg	$1,980	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
Species	Human
Expression System	E. coli
Tag	C-6xHis
Accession Number	Q02790
Amino Acid	Met1-Ala459
Construction	Met1-Ala459
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 10% Glycerol, pH 8.0.
Synonyms	Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP4, immunophilin FKBP52, HSP-binding immunophilin, FKBP59, FKBP4, FK506-binding protein 4, 59kDa immunophilin, 51kDa FK506-binding protein
Research Background	FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.

Chemical Properties

Molecular Weight

50-60 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.