Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, <33.3 μM, respectively. KRAS inhibitor-14 has potential to be investigated in pancreatic, colorectal and lung cancers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 2,140.00 | |
50 mg | 8-10 weeks | $ 2,785.00 | |
100 mg | 8-10 weeks | $ 3,520.00 |
Description | KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, >33.3 μM, respectively. KRAS inhibitor-14 has potential to be investigated in pancreatic, colorectal and lung cancers. |
Molecular Weight | 486.77 |
Formula | C20H15Cl3FN3O2S |
CAS No. | 2230873-78-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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KRAS inhibitor-14 2230873-78-4 inhibitor inhibit