MAGOH Protein, Human, Recombinant (His)

Catalog No. TMPY-01557 Copy Product Info

MAGOH (Mago Homolog, Exon Junction Complex Subunit) is a Protein Coding gene. MAGOH is the human homolog of Drosophila mago nashi, a protein that is required for normal germplasm development in the Drosophila embryo. In mammals, mRNA expression is not limited to the germplasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. The exon junction complex (EJCs) are deposited on messenger RNAs (mRNAs) during splicing and their core consists of eIF4A3, MLN51, Y14, and MAGOH. Both MAGOH proteins interact with other EJC components, incorporate into mRNA-bound EJCs, and activate nonsense-mediated decay. Diseases associated with MAGOH include Metaphyseal Chondrodysplasia, Schmid Type, and Primary Autosomal Recessive Microcephaly.

MAGOH Protein, Human, Recombinant (His)

Catalog No. TMPY-01557

Copy Product Info

Pack Size	Price	USA Stock	Global Stock
5 μg	$68	7-10 days	7-10 days
10 μg	$108	7-10 days	7-10 days
20 μg	$178	7-10 days	7-10 days
50 μg	$359	7-10 days	7-10 days
100 μg	$696	7-10 days	7-10 days

Add to Cart

Add to Quotation

For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Resource Download

User Guide of Recombinant Proteins

Product Information

Biological Activity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	MAGOH (Mago Homolog, Exon Junction Complex Subunit) is a Protein Coding gene. MAGOH is the human homolog of Drosophila mago nashi, a protein that is required for normal germplasm development in the Drosophila embryo. In mammals, mRNA expression is not limited to the germplasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. The exon junction complex (EJCs) are deposited on messenger RNAs (mRNAs) during splicing and their core consists of eIF4A3, MLN51, Y14, and MAGOH. Both MAGOH proteins interact with other EJC components, incorporate into mRNA-bound EJCs, and activate nonsense-mediated decay. Diseases associated with MAGOH include Metaphyseal Chondrodysplasia, Schmid Type, and Primary Autosomal Recessive Microcephaly.
Species	Human
Expression System	E. coli
Tag	C-His
Accession Number	P61326-1
Synonyms	mago-nashi homolog, proliferation-associated (Drosophila),MAGOHA,MAGOH1
Construction	A DNA sequence encoding the human MAGOH (NP_002361.1) (Met1-Ile146) was expressed with a polyhistide tag at the C-terminus. Predicted N terminal: Met
Protein Purity	> 90 % as determined by SDS-PAGE
Molecular Weight	18 kDa (predicted); 18 kDa (reducing conditions)
Endotoxin	Please contact us for more information.
Formulation	Supplied as sterile 137 mM NaCl, 2. 7 mM KCl, 10 mM Na2HPO4, 1. 8 mM KH2PO4, 20% glycerol, pH 4. 5.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	MAGOH (Mago Homolog, Exon Junction Complex Subunit) is a Protein Coding gene. MAGOH is the human homolog of Drosophila mago nashi, a protein that is required for normal germplasm development in the Drosophila embryo. In mammals, mRNA expression is not limited to the germplasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. The exon junction complex (EJCs) are deposited on messenger RNAs (mRNAs) during splicing and their core consists of eIF4A3, MLN51, Y14, and MAGOH. Both MAGOH proteins interact with other EJC components, incorporate into mRNA-bound EJCs, and activate nonsense-mediated decay. Diseases associated with MAGOH include Metaphyseal Chondrodysplasia, Schmid Type, and Primary Autosomal Recessive Microcephaly.