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Atacicept
(Synonyms: VT-001, VT001) Copy Product Info
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Synonyms: VT-001, VT001
Catalog No. T78302 Copy Product Info
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Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B-cell stimulation by binding to B-lymphocyte stimulatory factors and proliferation-inducing ligands, and can be used in the study of systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, multiple sclerosis, and various B-cell malignancies.
Atacicept
Cas No. 845264-92-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $448 | - | In Stock | |
| 5 mg | $1,170 | - | In Stock | |
| 10 mg | $1,870 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.9% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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| Description | Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B-cell stimulation by binding to B-lymphocyte stimulatory factors and proliferation-inducing ligands, and can be used in the study of systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, multiple sclerosis, and various B-cell malignancies. |
| In vivo | Atacicept (100 μg; intraperitoneal injection; three times per week for 14 days) significantly reduced the number of mature B cells and serum antibody levels in BALB/c mice. Atacicept (100 μg; intraperitoneal injection; three times per week for 21 days) effectively inhibited disease progression and autoantibody titers in a mouse model of collagen-induced arthritis (CIA).[1] |
| Synonyms | VT-001, VT001 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <0.9 EU/mg |
| Conjucates | Unconjugated |
| Target | APRIL/BAFF |
| Molecular Weight | 35.36 kDa |
| Cas No. | 845264-92-8 |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Atacicept in vivo | Atacicept molecular weight
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