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Atacicept (Synonyms: VT-001, VT001)

Catalog No. T78302 Copy Product Info
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Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B-cell stimulation by binding to B-lymphocyte stimulatory factors and proliferation-inducing ligands, and can be used in the study of systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, multiple sclerosis, and various B-cell malignancies.

Atacicept

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Catalog No. T78302
Synonyms VT-001, VT001

Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B-cell stimulation by binding to B-lymphocyte stimulatory factors and proliferation-inducing ligands, and can be used in the study of systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, multiple sclerosis, and various B-cell malignancies.

Atacicept
Cas No. 845264-92-8
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$448-In Stock
5 mg$1,170-In Stock
10 mg$1,870-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.9% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B-cell stimulation by binding to B-lymphocyte stimulatory factors and proliferation-inducing ligands, and can be used in the study of systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, multiple sclerosis, and various B-cell malignancies.
In vivo
Atacicept (100 μg; intraperitoneal injection; three times per week for 14 days) significantly reduced the number of mature B cells and serum antibody levels in BALB/c mice.
Atacicept (100 μg; intraperitoneal injection; three times per week for 21 days) effectively inhibited disease progression and autoantibody titers in a mouse model of collagen-induced arthritis (CIA).[1]
SynonymsVT-001, VT001
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<0.9 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetAPRIL/BAFF
Chemical Properties
Molecular Weight35.36 kDa
Cas No.845264-92-8
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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