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TFF1 Protein, Human, Recombinant (hFc)

(Synonyms: Trefoil factor 1, TFF1, PS2, Polypeptide P1.A, pNR-2, HPS2, HP1.A, D21S21, Bcei) Copy Product Info

Synonyms: Trefoil factor 1, TFF1, PS2, Polypeptide P1.A, pNR-2, HPS2, HP1.A, D21S21, Bcei

Catalog No. TMPK-00007 Copy Product Info
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 33.3 kDa and the accession number is P04155.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$517-10 days7-10 days
10 µg$807-10 days7-10 days
20 µg$1297-10 days7-10 days
50 µg$2487-10 days7-10 days
100 µg$4187-10 days7-10 days
200 µg$7577-10 days7-10 days
500 µg$1,6707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 33.3 kDa and the accession number is P04155.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP04155
ConstructionGlu25-Phe84
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTrefoil factor 1, TFF1, PS2, Polypeptide P1.A, pNR-2, HPS2, HP1.A, D21S21, Bcei
Research Background
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC.
Chemical Properties
Molecular Weight33.3 kDa (predicted). Due to glycosylation, the protein migrates to 40-45 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: TFF1 Protein, Human, Recombinant (hFc) chemical structure | TFF1 Protein, Human, Recombinant (hFc) molecular weight