Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GMB-475, also known as PROTAC BCR-ABL1 ligand 1, allosterically targets and binds to the BCR-ABL1 protein. It effectively recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1 [1].
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Description | GMB-475, also known as PROTAC BCR-ABL1 ligand 1, allosterically targets and binds to the BCR-ABL1 protein. It effectively recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1 [1]. |
Molecular Weight | 347.29 |
Formula | C17H12F3N3O2 |
CAS No. | 2489876-34-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC BCR-ABL1 ligand 1 2489876-34-6 inhibitor inhibit