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Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that obstructs tubulin polymerization, triggers apoptosis, and arrests MCF-7 breast cancer cells in the G2/M phase, demonstrating potent anti-proliferative activity with an IC50 of 10 nM [1].
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| Description | Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that obstructs tubulin polymerization, triggers apoptosis, and arrests MCF-7 breast cancer cells in the G2/M phase, demonstrating potent anti-proliferative activity with an IC50 of 10 nM [1]. |
| In vitro | Tubulin polymerization inhibitor 46 (compound 9q) at a concentration of 0.5 μM and an incubation time of 16 hours can induce microtubule network disassembly in MCF-7 breast cancer cells [1]. |
| Molecular Weight | 399.44 |
| Formula | C22H25NO6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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