Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-B7-H3 Antibody-PE (7G630)

🥰Excellent
Catalog No. TMAY-01732P

Anti-B7-H3 Antibody-PE (7G630) is a PE-conjugated Mouse antibody targeting B7-H3. Anti-B7-H3 Antibody-PE (7G630) can be used in FCM.

Anti-B7-H3 Antibody-PE (7G630)

Anti-B7-H3 Antibody-PE (7G630)

🥰Excellent
Catalog No. TMAY-01732P
Anti-B7-H3 Antibody-PE (7G630) is a PE-conjugated Mouse antibody targeting B7-H3. Anti-B7-H3 Antibody-PE (7G630) can be used in FCM.
TargetMol
Product information is being updated, if you want to purchase, please click the bulk custom button.
Bulk & Custom
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-B7-H3 Antibody-PE (7G630) is a PE-conjugated Mouse antibody targeting B7-H3. Anti-B7-H3 Antibody-PE (7G630) can be used in FCM.
Ig Type
Monoclonal Mouse IgG2b
Clone
7G630
Reactivity
Human
Verified Activity
Flow cytometric analysis of anti-B7H3 (CD276) reactivity on PC-3 cells.
Application
FCM
Recommended Dose
2 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human B7-H3 / CD276 (rh B7-H3 / CD276; TMPY-02031; Q5ZPR3-1; Met 1-Thr 461) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundB7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/APC/FITC/HRP
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Human B7-H3 / CD276 protein (TMPY-02031)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-B7-H3 Antibody-PE (7G630) | purchase Anti-B7-H3 Antibody-PE (7G630) | Anti-B7-H3 Antibody-PE (7G630) cost | order Anti-B7-H3 Antibody-PE (7G630)