Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating antiproliferative activity. It activates caspase-3 and cleaved poly ADP-ribose polymerase, inducing apoptosis. Furthermore, DPP enhances the maturation and antigen presentation of dendritic cells and exhibits in vivo safety [1].
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Description | DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating antiproliferative activity. It activates caspase-3 and cleaved poly ADP-ribose polymerase, inducing apoptosis. Furthermore, DPP enhances the maturation and antigen presentation of dendritic cells and exhibits in vivo safety [1]. |
Molecular Weight | 926.7 |
Formula | C36H40Cl2N2O10Pt |
CAS No. | 2668267-47-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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DPP 2668267-47-6 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells JAK inhibitor inhibit