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ROR2 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00577
Synonyms: NTRKR2, ROR2, BDB1, BDB

ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. ROR2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 44.2 kDa and the accession number is A1L4F5.

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ROR2 Protein, Human, Recombinant (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. ROR2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 44.2 kDa and the accession number is A1L4F5.
Species Human
Expression System HEK293
Tag C-His-Avi
Accession Number A1L4F5
Synonyms NTRKR2, ROR2, BDB1, BDB
Construction Recombinant Human ROR2/NTRKR2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Val34-Gly403.[Accession |A1L4F5]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 44.2 kDa. Due to glycosylation, the protein migrates to 54-58 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.

References and Literature

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Keywords

ROR2 Protein, Human, Recombinant (His & Avi) NTRKR 2 ROR 2 NTRKR2 NTRKR-2 ROR2 BDB-1 ROR-2 BDB1 BDB 1 BDB recombinant recombinant-proteins proteins protein

 

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