Powder: -20°C for 3 years | In solvent: -80°C for 1 year
14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid .114S(15R)-EET binds to isolated guinea pig monocytes with a Kivalue of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.2It induces dilation of precontracted isolated canine epicardial arterioles (EC50= 4 pM) and denuded porcine subepicardial arterioles (EC50= 3 pM).3Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.4
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Description | 14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid .114S(15R)-EET binds to isolated guinea pig monocytes with a Kivalue of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.2It induces dilation of precontracted isolated canine epicardial arterioles (EC50= 4 pM) and denuded porcine subepicardial arterioles (EC50= 3 pM).3Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.4 |
Molecular Weight | 320.473 |
Formula | C20H32O3 |
CAS No. | 105304-92-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
You can also refer to dose conversion for different animals. More
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14S(15R)-EET 105304-92-5 14SEET 14S(15R) EET 14S(15R)EET inhibitor inhibit