CTH Protein, Human, Recombinant

Name: CTH Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-00939
Rating: 4.5 (1 reviews)

(Synonyms: γ-Cystathionase, Gamma-Cystathionase, Cysteine-Protein Sulfhydrase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH) Copy Product Info

Synonyms: γ-Cystathionase, Gamma-Cystathionase, Cysteine-Protein Sulfhydrase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH

Catalog No. TMPJ-00939 Copy Product Info

Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

Pack Size	Price	USA Stock	Global Stock
10 µg	$116	7-10 days	7-10 days
20 µg	$186	7-10 days	7-10 days
50 µg	$352	7-10 days	7-10 days
100 µg	$582	7-10 days	7-10 days
200 µg	$967	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P32929
Amino Acid	Met1-Ser405
Construction	Met1-Ser405
Protein Purity	Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH8.0.
Synonyms	γ-Cystathionase, Gamma-Cystathionase, Cysteine-Protein Sulfhydrase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH
Research Background	Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

Chemical Properties

Molecular Weight

38-50 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.