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CTH Protein, Human, Recombinant

Catalog No. TMPJ-00939
Synonyms: γ-Cystathionase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH, Cysteine-Protein Sulfhydrase, Gamma-Cystathionase

Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CTH Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 352.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.
Species Human
Expression System E. coli
Tag None
Accession Number P32929
Synonyms γ-Cystathionase, Cystathionine γ-Lyase, Cystathionine Gamma-Lyase, CTH, Cysteine-Protein Sulfhydrase, Gamma-Cystathionase
Amino Acid Met1-Ser405
Construction Recombinant Human Cystathionine Gamma-Lyase is produced by our E.coli expression system and the target gene encoding Met1-Ser405 is expressed.
Protein Purity Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 38-50 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

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Keywords

CTH Protein, Human, Recombinant γ-Cystathionase Cystathionine γ-Lyase Cystathionine Gamma-Lyase CTH Cysteine-Protein Sulfhydrase Gamma-Cystathionase recombinant recombinant-proteins proteins protein

 

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