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Vorapaxar sulfate (Alias: Zontivity, vorapaxar monosulfate, SCH 530348 sulfate)

Catalog No. T3098 Copy Product Info
Purity: 99.99%
🥰Excellent
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.

Vorapaxar sulfate

Copy Product Info
🥰Excellent
Catalog No. T3098
Alias Zontivity, vorapaxar monosulfate, SCH 530348 sulfate

Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.

Vorapaxar sulfate
Cas No. 705260-08-8
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$32In StockIn Stock
2 mg$45In StockIn Stock
5 mg$72In StockIn Stock
10 mg$122In StockIn Stock
25 mg$222In StockIn Stock
50 mg$372In StockIn Stock
100 mg$556In StockIn Stock
500 mg$1,220-In Stock
1 mL x 10 mM (in DMSO)$100In StockIn Stock
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.99%
Color:White
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Product Introduction

Bioactivity
Description
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.
Targets&IC50
PAR1:8.1 nM (Ki)
SynonymsZontivity, vorapaxar monosulfate, SCH 530348 sulfate
Chemical Properties
Molecular Weight590.66
FormulaC29H35FN2O8S
Cas No.705260-08-8
SmilesOS(O)(=O)=O.[H][C@@]12C[C@]3([H])C[C@@H](CC[C@@]3([H])[C@H](\C=C\c3ccc(cn3)-c3cccc(F)c3)[C@]1([H])[C@@H](C)OC2=O)NC(=O)OCC
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 245 mg/mL (414.79 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6930 mL8.4651 mL16.9302 mL84.6511 mL
5 mM0.3386 mL1.6930 mL3.3860 mL16.9302 mL
10 mM0.1693 mL0.8465 mL1.6930 mL8.4651 mL
20 mM0.0847 mL0.4233 mL0.8465 mL4.2326 mL
50 mM0.0339 mL0.1693 mL0.3386 mL1.6930 mL
100 mM0.0169 mL0.0847 mL0.1693 mL0.8465 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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