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Anti-TNFAIP8 Antibody (7K95) is a Mouse antibody targeting TNFAIP8. Anti-TNFAIP8 Antibody (7K95) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-TNFAIP8 Antibody (7K95) is a Mouse antibody targeting TNFAIP8. Anti-TNFAIP8 Antibody (7K95) can be used in IHC-P. |
Alias | tumor necrosis factor, α-induced protein 8, tumor necrosis factor, alpha-induced protein 8, SCC-S2, SCCS2, NDED, MDC-3.13, GG2-1 |
Ig Type | Monoclonal Mouse IgG2b |
Clone | 7K95 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human TNFAIP8 in human placenta with mouse monoclonal antibody at 1:10000 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human TNFAIP8 in human spleen with mouse monoclonal antibody at 1:10000 dilution, formalin-fixed paraffin embedded sections. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:1000-1:20000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNFAIP8 (rh TNFAIP8; TMPY-03416; O95379; Met1-Ile198). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-alpha inducible anti-apoptotic protein with multiple roles in tumor growth and survival. by the creation of cellular autophagy events, TNFAIP8 promotes cell survival and drug resistance in prostate cancer cells. TNFAIP8 regulates Hippo pathway through interacting with LATS1 to promote cell proliferation and invasion in lung cancer. TNFAIP8 may serve as a candidate biomarker for poor prognosis and a target for new therapies. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human TNFAIP8 protein (TMPY-03416) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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