PCSK9 Protein, Human, Recombinant (Avi), Biotinylated

Name: PCSK9 Protein, Human, Recombinant (Avi), Biotinylated
Brand: TargetMol
SKU: TMPJ-00368
Rating: 4.5 (1 reviews)

(Synonyms: Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9, Neural Apoptosis-Regulated Convertase 1, NARC-1, NARC1) Copy Product Info

Synonyms: Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9, Neural Apoptosis-Regulated Convertase 1, NARC-1, NARC1

Catalog No. TMPJ-00368 Copy Product Info

PCSK9 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19&65 KDa and the accession number is Q8NBP7.

Pack Size	Price	USA Stock	Global Stock
10 µg	$213	35 days	35 days
20 µg	$355	35 days	35 days
50 µg	$625	35 days	35 days
100 µg	$963	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Liquid

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	PCSK9 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19&65 KDa and the accession number is Q8NBP7.
Species	Human
Expression System	HEK293 Cells
Tag	C-Avi
Accession Number	Q8NBP7
Amino Acid	Gln31-Gln692(Val474Ile,Gly670Glu)
Construction	Gln31-Gln692(Val474Ile,Gly670Glu)
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 20% Glycerol, pH 7.4.
Synonyms	Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9, Neural Apoptosis-Regulated Convertase 1, NARC-1, NARC1
Research Background	Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.

Chemical Properties

Molecular Weight

19&65 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Dose Conversion

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Tech Support

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Keywords

PCSK-9PCSK 9PC-9PC 9NARC 1

Related Tags: PCSK9 Protein, Human, Recombinant (Avi), Biotinylated chemical structure | PCSK9 Protein, Human, Recombinant (Avi), Biotinylated molecular weight