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IA2 Protein, Human, Recombinant (aa 687-979, His)
(Synonyms: R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N, PTPRN, PTP IA-2, Islet cell autoantigen 3, Islet cell antigen 512, ICA512, ICA3, ICA 512) Copy Product InfoSynonyms: R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N, PTPRN, PTP IA-2, Islet cell autoantigen 3, Islet cell antigen 512, ICA512, ICA3, ICA 512
Catalog No. TMPJ-01141 Copy Product Info
IA2 Protein, Human, Recombinant (aa 687-979, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is Q16849.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $183 | 7-10 days | 7-10 days | |
| 20 µg | $292 | 7-10 days | 7-10 days | |
| 50 µg | $545 | 7-10 days | 7-10 days | |
| 100 µg | $792 | 7-10 days | 7-10 days | |
| 200 µg | $1,150 | 7-10 days | 7-10 days | |
| 500 µg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,970 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | IA2 Protein, Human, Recombinant (aa 687-979, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is Q16849. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | Q16849 |
| Amino Acid | Met687-Gln979 |
| Construction | Met687-Gln979 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0. |
| Synonyms | R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N, PTPRN, PTP IA-2, Islet cell autoantigen 3, Islet cell antigen 512, ICA512, ICA3, ICA 512 |
| Research Background | Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. |
| Molecular Weight | 33 KDa (reducing condition) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IA2 Protein, Human, Recombinant (aa 687-979, His) chemical structure | IA2 Protein, Human, Recombinant (aa 687-979, His) molecular weight
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