TDT Protein, Human, Recombinant (His)

Name: TDT Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00765
Rating: 4.5 (1 reviews)

(Synonyms: Terminal transferase, Terminal deoxynucleotidyltransferase, Terminal deoxynucleotidyltr, Terminal addition enzyme, TDT, DNTT, DNA nucleotidylexotransferase) Copy Product Info

Synonyms: Terminal transferase, Terminal deoxynucleotidyltransferase, Terminal deoxynucleotidyltr, Terminal addition enzyme, TDT, DNTT, DNA nucleotidylexotransferase

Catalog No. TMPJ-00765 Copy Product Info

Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
10 µg	$153	7-10 days	7-10 days
20 µg	$246	7-10 days	7-10 days
50 µg	$465	7-10 days	7-10 days
100 µg	$753	7-10 days	7-10 days
200 µg	$1,220	7-10 days	7-10 days
500 µg	$2,330	7-10 days	7-10 days
1 mg	$3,490	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	P04053
Amino Acid	Met1-Ala509
Construction	Met1-Ala509
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 0.1M KH<sub>2</sub>PO<sub>4</sub>, 200 mM KCl, 1 mM 2-Mercaptoethanol, 50% Glycerol, pH 7.2.
Synonyms	Terminal transferase, Terminal deoxynucleotidyltransferase, Terminal deoxynucleotidyltr, Terminal addition enzyme, TDT, DNTT, DNA nucleotidylexotransferase
Research Background	Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

Chemical Properties

Molecular Weight

62 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.