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Caprin-1/CAPRIN1 Protein, Human, Recombinant (His)

Catalog No. TMPH-01036
Synonyms: GPI-anchored membrane protein 1, CAPRIN1, GPIP137, M11S1, GPI-anchored protein p137, Membrane component chromosome 11 surface marker 1, RNA granule protein 105, Caprin-1, Cell cycle-associated protein 1, RNG105, Cytoplasmic activation- and proliferation-associated protein 1, p137GPI, GPI-p137, GPIAP1

May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Caprin-1/CAPRIN1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 491.00
100 μg 20 days $ 1,370.00
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Biological Description
Technical Params
Product Properties
Description May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Species Human
Expression System Baculovirus
Tag N-terminal 10xHis-tagged
Accession Number Q14444
Synonyms GPI-anchored membrane protein 1, CAPRIN1, GPIP137, M11S1, GPI-anchored protein p137, Membrane component chromosome 11 surface marker 1, RNA granule protein 105, Caprin-1, Cell cycle-associated protein 1, RNG105, Cytoplasmic activation- and proliferation-associated protein 1, p137GPI, GPI-p137, GPIAP1
Amino Acid PSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPRDYSGYQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 2-709 aa
Protein Purity > 85% as determined by SDS-PAGE.
Molecular Weight 80.7 kDa (predicted)
Formulation Tris-based buffer，50% glycerol
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

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Keywords

Caprin-1/CAPRIN1 Protein, Human, Recombinant (His) GPI-anchored membrane protein 1 CAPRIN1 GPIP137 M11S1 GPI-anchored protein p137 Membrane component chromosome 11 surface marker 1 RNA granule protein 105 Caprin-1 Cell cycle-associated protein 1 RNG105 Cytoplasmic activation- and proliferation-associated protein 1 p137GPI GPI-p137 GPIAP1 recombinant recombinant-proteins proteins protein

 

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