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EGF Receptor Peptide Acetate

Name: EGF Receptor Peptide Acetate
Brand: TargetMol
SKU: T21723L
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21723L

Alias Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base), EGF Receptor Peptide Acetate (96249-43-3 Free base)

Epidermal Growth Factor Receptor Peptide Acetate exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK).

EGF Receptor Peptide Acetate

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Purity: 98.81%

Catalog No. T21723LAlias Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base), EGF Receptor Peptide Acetate (96249-43-3 Free base)

Epidermal Growth Factor Receptor Peptide Acetate exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$41	In Stock	In Stock
2 mg	$56	In Stock	In Stock
5 mg	$117	In Stock	In Stock
10 mg	$197	In Stock	In Stock
25 mg	$286	In Stock	In Stock
50 mg	$429	In Stock	In Stock
100 mg	$635	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$297	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.81%

Appearance:Solid

Color:White

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COA MS HPLC

Product Introduction

Bioactivity

Description	Epidermal Growth Factor Receptor Peptide Acetate exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK).
In vitro	This autophosphorylation elicits downstream activation and signaling by several other proteins that associate with the phosphorylated tyrosines through their own phosphotyrosine-binding SH2 domains.?These downstream signaling proteins initiate several signal transduction cascades, principally the MAPK, Akt and JNK pathways, which lead to DNA synthesis and cell proliferation.Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation.?Activation of the receptor is important for the innate immune response in human skin.?
Synonyms	Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base), EGF Receptor Peptide Acetate (96249-43-3 Free base)

Chemical Properties

Molecular Weight	1436.52
Formula	C₆₃H₉₇N₁₃O₂₅
Smiles	O=C(N)CC[C@@H](C(O)=O)NC([C@H]1N(C([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](CC(O)=O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O.CC(O)=O
Relative Density.	no data available
Sequence	H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH
Sequence Short	DVVDADEYLIPQ

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 10 mg/mL (6.96 mM), Sonication is recommended.

DMSO: 133 mg/mL (92.58 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	0.6961 mL	3.4806 mL	6.9613 mL	34.8063 mL
5 mM	0.1392 mL	0.6961 mL	1.3923 mL	6.9613 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.0696 mL	0.3481 mL	0.6961 mL	3.4806 mL
20 mM	0.0348 mL	0.1740 mL	0.3481 mL	1.7403 mL
50 mM	0.0139 mL	0.0696 mL	0.1392 mL	0.6961 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc