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CDH3 Protein, Human, Recombinant (aa 108-654, His)
(Synonyms: Placental cadherin, PCADP-cadherin, P-cadherin, PCAD, HJMD, CDHP, CDH3, Cadherin-3, CAD3) Copy Product InfoSynonyms: Placental cadherin, PCADP-cadherin, P-cadherin, PCAD, HJMD, CDHP, CDH3, Cadherin-3, CAD3
Catalog No. TMPK-00851 Copy Product Info
Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration. CDH3 Protein, Human, Recombinant (aa 108-654, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.32 kDa and the accession number is P22223-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $58 | 7-10 days | 7-10 days | |
| 10 μg | $92 | - | In Stock | |
| 20 μg | $148 | 7-10 days | 7-10 days | |
| 50 μg | $289 | - | In Stock | |
| 100 μg | $487 | - | In Stock | |
| 200 μg | $883 | 7-10 days | 7-10 days | |
| 500 μg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
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Purity:> 95% as determined by Bis-Tris PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Anti-CDH3 Antibody, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human CDH3, His Tag with the EC50 of 2.1μg/ml determined by ELISA. |
| Description | Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration. CDH3 Protein, Human, Recombinant (aa 108-654, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.32 kDa and the accession number is P22223-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P22223-1 |
| Construction | Asp108-Gly654 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Placental cadherin, PCADP-cadherin, P-cadherin, PCAD, HJMD, CDHP, CDH3, Cadherin-3, CAD3 |
| Research Background |
| Molecular Weight | 64.32 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CDH3 Protein, Human, Recombinant (aa 108-654, His) chemical structure | CDH3 Protein, Human, Recombinant (aa 108-654, His) molecular weight
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