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CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $46 | 7-10 days | |
| 10 μg | $72 | 7-10 days | |
| 20 μg | $115 | 7-10 days | |
| 50 μg | $222 | 7-10 days | |
| 100 μg | $371 | 7-10 days | |
| 200 μg | $673 | 7-10 days | |
| 500 μg | $1,490 | 7-10 days |
| Biological Activity | Immobilized Human CD155, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human TIGIT, hFc Tag with the EC50 0.5μg/ml determined by ELISA. |
| Description | CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | P15151-1 |
| Synonyms | Tage4,PVSFLJ25946,PVS,PVR,nectin-like 5,Necl-5,NECL5,HVED,FLJ25946,CD155 |
| Construction | Trp21-Asn343 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC |
| Molecular Weight | 38 kDa (predicted). Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result. |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. |
| Research Background | CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR. |

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