Anti-Phospho-BRAF (Ser365) Polyclonal Antibody

Name: Anti-Phospho-BRAF (Ser365) Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-01396
Rating: 4.5 (1 reviews)

(Synonyms: v-Raf murine sarcoma viral oncogene homolog B1, Serine/threonine-protein kinase B-raf, RAFB1, Proto-oncogene B-Raf, p-BRAF (Ser365), p-BRAF (S365), p94, EC 2.7.11.1, BRAF1, BRAF (p-Ser365), BRAF (p-S365)) Copy Product Info

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Synonyms: v-Raf murine sarcoma viral oncogene homolog B1, Serine/threonine-protein kinase B-raf, RAFB1, Proto-oncogene B-Raf, p-BRAF (Ser365), p-BRAF (S365), p94, EC 2.7.11.1, BRAF1, BRAF (p-Ser365), BRAF (p-S365)

Catalog No. TMAB-01396 Copy Product Info

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Anti-Phospho-BRAF (Ser365) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRAF (Ser365). Anti-Phospho-BRAF (Ser365) Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.

Anti-Phospho-BRAF
(Ser365) Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$222	7-10 days	7-10 days
100 μL	$374	7-10 days	7-10 days
200 μL	$527	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-Phospho-BRAF (Ser365) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BRAF (Ser365). Anti-Phospho-BRAF (Ser365) Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
Synonyms	v-Raf murine sarcoma viral oncogene homolog B1, Serine/threonine-protein kinase B-raf, RAFB1, Proto-oncogene B-Raf, p-BRAF (Ser365), p-BRAF (S365), p94, EC 2.7.11.1, BRAF1, BRAF (p-Ser365), BRAF (p-S365)
Ig Type	IgG
Reactivity	Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit)

Application	IF IHC-Fr IHC-P
Recommended Dose	IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Nucleus. Cytoplasm. Cell membrane.
Tissue Specificity	Brain and testis.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]

Antigen Details

Immunogen	KLH conjugated Synthesised phosphopeptide: human BRAF around the phosphorylation site of Ser365
Antigen Species	Human
Gene Name	BRAF
Gene ID	673
Protein Name	Serine/threonine-protein kinase B-raf
Uniprot ID	P15056
Biology Area	Signal transducers,Kinases,Cell differentiation,Other Kinases,Tyrosine Kinases
Function	Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.