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Synonyms: PODXL1, PDX, PCLP-1, PCLP1, PCLP, PC, Gp200, gp135


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $77 | 7-10 days | 7-10 days | |
| 10 µg | $126 | 7-10 days | 7-10 days | |
| 20 µg | $198 | 7-10 days | 7-10 days | |
| 50 µg | $397 | 7-10 days | 7-10 days | |
| 100 µg | $796 | 7-10 days | 7-10 days | |
| 200 µg | $1,200 | 7-10 days | 7-10 days | |
| 500 µg | $2,590 | 7-10 days | 7-10 days | |
| 1 mg | $5,280 | 7-10 days | 7-10 days |
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | PODXL Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is O00592. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | O00592 |
| Construction | A DNA sequence encoding the Human PODXL (O00592) (Ser23-Pro461) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Protein Purity | ≥ 90% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Please refer to the lot-specific COA. |
| Synonyms | PODXL1, PDX, PCLP-1, PCLP1, PCLP, PC, Gp200, gp135 |
| Research Background | Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer. |
| Molecular Weight | 72.06 kDa (predicted); 146.2 kDa (reducing contition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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