Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

16(S)-Iloprost

Name: 16(S)-Iloprost
Brand: TargetMol
SKU: T36212
Rating: 4.5 (1 reviews)

Copy Product Info

😃Good

Catalog No. T36212Cas No. 74843-14-4

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(S)-Iloprost potently inhibits platelet aggregation with an IC50 value of 3.5 nM.

16(S)-Iloprost

Copy Product Info

😃Good

Catalog No. T36212Cas No. 74843-14-4

Pack Size	Price	USA Warehouse	Global Warehouse
500 μg	$812	35 days	35 days
1 mg	$1,530	35 days	35 days
5 mg	$6,430	35 days	35 days

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Resource Download

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	360.49
Formula	C₂₂H₃₂O₄
Cas No.	74843-14-4
Smiles	C(=C/[C@H]([C@H](CC#CC)C)O)\[C@@H]1[C@@]2([C@@](C/C(=C\CCCC(O)=O)/C2)(C[C@H]1O)[H])[H]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 30 mg/mL (83.22 mM), Sonication is recommended.

Ethanol: 30 mg/mL (83.22 mM), Sonication is recommended.

PBS (pH 7.2): 1 mg/mL (2.77 mM), Sonication is recommended.

DMSO: 25 mg/mL (69.35 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/DMF/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.7740 mL	13.8700 mL	27.7400 mL	138.7001 mL

DMSO/DMF/Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.5548 mL	2.7740 mL	5.5480 mL	27.7400 mL
10 mM	0.2774 mL	1.3870 mL	2.7740 mL	13.8700 mL
20 mM	0.1387 mL	0.6935 mL	1.3870 mL	6.9350 mL
50 mM	0.0555 mL	0.2774 mL	0.5548 mL	2.7740 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc