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Anti-GAP43 Polyclonal Antibody
😃Good
Catalog No. TMAB-00740
Alias PP46, growth associated protein 43, B-50
Anti-GAP43 Polyclonal Antibody is a Rabbit antibody targeting GAP43. Anti-GAP43 Polyclonal Antibody can be used in IF,IHC-Fr.
Anti-GAP43 Polyclonal Antibody
Anti-GAP43 Polyclonal Antibody
😃Good
Catalog No. TMAB-00740Alias PP46, growth associated protein 43, B-50
Anti-GAP43 Polyclonal Antibody is a Rabbit antibody targeting GAP43. Anti-GAP43 Polyclonal Antibody can be used in IF,IHC-Fr.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GAP43 Polyclonal Antibody is a Rabbit antibody targeting GAP43. Anti-GAP43 Polyclonal Antibody can be used in IF,IHC-Fr. |
| Synonyms | PP46, growth associated protein 43, B-50 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (GAP43) Polyclonal Antibody, Unconjugated (TMAB-00740) at 1:400 overnight at 4°C, followed by a conjugated Goat Anti-Rabbit IgG antibody for 90 minutes, and DAPI for nucleus staining. 2. Paraformaldehyde-fixed, paraffin embedded (Human glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (GAP43) Polyclonal Antibody, Unconjugated (TMAB-00740) at 1:400 overnight at 4°C, followed by a conjugated Goat Anti-Rabbit IgG antibody for 90 minutes, and DAPI for nucleus staining.   |
| Application | |
| Recommended Dose | IHC-Fr: 1:100-500; IF: 1:200-800 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human GAP43 |
| Antigen Species | Human |
| Gene Name | GAP43 |
| Gene ID | |
| Protein Name | Neuromodulin |
| Uniprot ID | |
| Biology Area | Growth Cone,Synapse marker,Axonal Guidance Proteins |
| Function | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. |
| Molecular Weight | Theoretical: 25/46 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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